How long can short-acting insulin last in the body?

Short-acting insulin typically peaks in action around 2 to 4 hours after administration and can last in the body for approximately 6 to 8 hours. Therefore, the correct range for its overall duration of effect generally aligns with the answer that indicates it can last up to 12 hours.

Understanding pharmacokinetics is crucial in this context. Short-acting insulin, such as regular insulin, is designed for effective management of blood glucose levels after meals. Knowing that it remains active in the body for approximately 6 to 8 hours helps healthcare providers determine the timing of administration to optimally match insulin activity with blood glucose peaks that occur after eating.

While other durations, such as those indicated in the alternative choices, may relate to different types of insulin, they do not accurately reflect the effectiveness and duration of action typical for short-acting insulin.